2009

Trieber C.A., Afara M.R., Young H.S. (2009) Effects of phospholamban transmembrane mutants on the calcium affinity, maximal activity and cooperativity of the sarcoplasmic reticulum calcium pump. Biochemistry 48 (39): 9287-9296.

Catalucci D., Latronico M.V., Ceci M., Rusconi F., Young H.S., Gallo P., Santonastasi M., Bellacosa A., Heller Brown J., Condorelli G. (2009) AKT increases sarcoplasmic reticulum Ca2+ cycling by direct phosphorylation of phospholamban (PLN) at THR17. J Biol Chem. 284 (41): 28180-28187.

Laursen M., Bublitz M., Moncoq K., Olesen C., Møller J.V., Young H.S., Nissen P., Morth J.P. (2009) Cyclopiazonic Acid Is Complexed to a Divalent Metal Ion When Bound to the Sarcoplasmic Reticulum Ca2+-ATPase. J Biol Chem. 284 (20): 13513-13518.

Ogawa H., Qiu Y., Huang L., Tam-Chang S.W., Young H.S., Misono K.S. (2009) Structure of the atrial natriuretic peptide receptor extracellular domain in the unbound and hormone-bound states by single-particle electron microscopy. FEBS J. 276 (5): 1347-1355.

2008

Afara M.R., Trieber C.A., Ceholski D.K.,Young H.S. (2008) Peptide inhibitors use two related mechanisms to alter the apparent calcium affinity of the sarcoplasmic reticulum calcium pump. Biochemistry 47 (36): 9522-9530.

Seidel K., Andronesi O.C., Krebs J., Griesinger C., Young H.S., Becker S., Baldus M. (2008) Structural characterization of Ca(2+)-ATPase-bound phospholamban in lipid bilayers by solid-state nuclear magnetic resonance (NMR) spectroscopy. Biochemistry 47 (15): 4369-4376.

Moncoq K., Kemp G., Li X., Fliegel L., Young H.S. (2008) Dimeric structure of human Na+/H+ exchanger isoform 1 overproduced in Saccharomyces cerevisiae. J Biol Chem. 283 (7): 4145-4154.

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2007

Moncoq K., Trieber C.A., Young H.S. (2007) The molecular basis for cyclopiazonic acid inhibition of the sarcoplasmic reticulum calcium pump. J Biol Chem. 282 (13): 9748-9757.

2006

Afara M.R., Trieber C.A., Glaves J.P., Young H.S. (2006) Rational design of peptide inhibitors of the sarcoplasmic reticulum calcium pump. Biochemistry 45 (28): 8617-8627.

Stokes D.L., Pomfret A.J., Rice W.J., Glaves J.P., Young H.S. (2006) Interactions between Ca2+-ATPase and the pentameric form of phospholamban in two-dimensional co-crystals. Biophys J. 90 (11): 4213-4223.


2005

Andronesi O.C., Becker S., Seidel K., Heise H., Young H.S., Baldus M. (2005) Determination of membrane protein structure and dynamics by magic-angle-spinning solid-state NMR spectroscopy. J Am Chem Soc. 127 (37): 12965-12974.

Trieber C.A, Douglas J.L, Afara M., Young H.S. (2005) The effects of mutation on the regulatory properties of phospholamban in co-reconstituted membranes. Biochemistry 44 (9): 3289-3297.

Douglas J.L., Trieber C.A., Afara M., Young H.S. (2005) Rapid, high-yield expression and purification of Ca2+-ATPase regulatory proteins for high-resolution structural studies. Protein Expr Purif. 40 (1): 118-125.

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2004

Young H.S., Stokes D.L. (2004) The mechanics of calcium transport. J Membr Biol. 198 (2): 55-63. (Review)

2003

Young H.S., Herbette L.G., Skita V. (2003) Alpha-bungarotoxin binding to acetylcholine receptor membranes studied by low angle X-ray diffraction. Biophys J. 85 (2): 943-953.

Young H.S., Dang H., Lai Y., DeRosier D.J., Khan S. (2003) Variable symmetry in Salmonella typhimurium flagellar motors. Biophys J. 84 (1): 571-577.

2001

Young H.S., Jones L.R, Stokes D.L. (2001) Locating phospholamban in co-crystals with Ca(2+)-ATPase by cryoelectron microscopy. Biophys J. 81 (2): 884-894.

Young H.S., Xu C., Zhang P., Stokes D.L. (2001) Locating the thapsigargin-binding site on Ca(2+)-ATPase by cryoelectron microscopy. J Mol Biol. 308 (2): 231-240.

Rice W.J., Young H.S., Martin D.W., Sachs J.R., Stokes D.L. (2001) Structure of Na+,K+-ATPase at 11-A resolution: comparison with Ca2+-ATPase in E1 and E2 states. Biophys J. 80 (5): 2187-2197.

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1998

Young H.S., Reddy L.G., Jones L.R., Stokes D.L. (1998) Co-reconstitution and co-crystallization of phospholamban and Ca(2+)-ATPase. Ann N.Y. Acad Sci. 853: 103-115.

Shi D., Lewis M.R., Young H.S., Stokes D.L. (1998) Three-dimensional crystals of Ca2+-ATPase from sarcoplasmic reticulum: merging electron diffraction tilt series and imaging the (h, k, 0) projection. J Mol Biol. 284 (5): 1547-1564.

1997

Young H.S., Rigaud J.L., Lacapère J.J., Reddy L.G., Stokes D.L. (1997) How to make tubular crystals by reconstitution of detergent-solubilized Ca2(+)-ATPase. Biophys J. 72 (6): 2545-2558.

1996

Cheong G.W., Young H.S., Ogawa H., Toyoshima C., Stokes D.L. (1996) Lamellar stacking in three-dimensional crystals of Ca(2+)-ATPase from sarcoplasmic reticulum. Biophys J. 70 (4): 1689-1699.

1992

Chester D.W., Skita V., Young H.S., Mavromoustakos T., Strittmatter P. (1992) Bilayer structure and physical dynamics of the cytochrome b5 dimyristoylphosphatidylcholine interaction. Biophys J. 61 (5): 1224-1243.

Young H.S., Skita V, Mason RP, Herbette LG. (1992) Molecular basis for the inhibition of 1,4-dihydropyridine calcium channel drugs binding to their receptors by a nonspecific site interaction mechanism. Biophys J. 61 (5): 1244-1255.

1988

Prasad M.R., Jones R.M., Young H.S., Kaplinsky LB, Das DK. (1988) Analysis of tissue free fatty acids isolated by aminopropyl bonded-phase columns. J Chromatogr. 428 (2): 221-228.

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